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研究成果

  為積極推廣健康資料研究至長庚醫院，提升臨床醫師、專任人員對健康資料應用研究之熱情，並鼓勵研究資源相對不足之年輕醫師或研究人員投入其研究，本中心向長庚醫院申請之多年期整合型計畫(CMRP)，結合專業研究群，提供協作服務並幫助已收集臨床資料之醫師與現有健康庫整合比對，拓展健康資料應用之加值效益，透過雙方合作與成果，提升長庚大學及長庚醫院之知名度，目前已有多篇論文發表，其中1篇研究成果於2018年2月發表於世界頂尖醫學期刊「美國醫學會雜誌（JAMA: The Journal of the American Medical Association）」，同時於校內的榮譽消息專區/長庚校訊做了報導 ─  靜脈曲張可能造成深層靜脈血栓之嚴重後果─長庚醫院與長庚大學研究合作榮登美國醫學會雜誌。

本中心CMRP現研究成果如下：

  1. Lin, H. C., C. C. Lai, P. W. Lin, M. Friedman, A. M. Salapatas, H. W. Chang, M. C. Lin and C. H. Chin (2019). "Clinical Prediction Model for Obstructive Sleep Apnea among Adult Patients with Habitual Snoring." Otolaryngol Head Neck Surg: 194599819839999.
  2. Yu, S.-F., J.-S. Cheng, Y.-C. Chen, J.-F. Chen, C.-Y. Hsu, H.-M. Lai, C.-H. Ko, W.-C. Chiu, Y.-J. Su and T.-T. Cheng (2019). "Adherence to anti-osteoporosis medication associated with lower mortality following hip fracture in older adults: a nationwide propensity score-matched cohort study." BMC Geriatrics 19(1): 290.
  3. Lin, H. C., J. R. Lin, W. C. Tsai, C. H. Lu, W. N. Chang, C. C. Huang, H. C. Wang, C. T. Kung, C. M. Su, Y. J. Su, W. C. Lin, B. C. Cheng, C. W. Hsu, Y. R. Lai and N. W. Tsai (2019). "The outcomes of statin therapy in patients with acute ischemic stroke in Taiwan: a nationwide epidemiologic study." Qjm 112(12): 891-899.
  4. Lee, C. H., C. J. Chang, Y. J. Lin, C. L. Yen, C. H. Shen, Y. T. Cheng, C. C. Lin and S. Y. Hsieh (2019). "Nomogram predicting extrahepatic metastasis of hepatocellular carcinoma based on commonly available clinical data." JGH Open 3(1): 38-45.
  5. Chen, C. H., C. B. Chen, C. J. Chang, Y. J. Lin, C. W. Wang, C. C. Chi, C. W. Lu, W. T. Chen, R. Y. Pan, S. C. Su, L. A. Hsu, Y. C. Chang, K. H. Yu, Y. J. Wu, K. M. Lin, S. I. Hung, S. M. Chen and W. H. Chung (2019). "Hypersensitivity and cardiovascular risks related to allopurinol and febuxostat therapy in Asians: A population-based cohort study and meta-analysis." Clin Pharmacol Ther.
  6. Lin, M. J., H. W. Chen, P. H. Liu, W. J. Cheng, S. L. Kuo and M. C. Kao (2019). "The prescription patterns of traditional Chinese medicine for women with polycystic ovary syndrome in Taiwan: A nationwide population-based study." Medicine (Baltimore) 98(24): e15890.
  7. Lin, S.-J., C.-W. Tung, Y.-C. Hsu, Y.-H. Shih, Y.-L. Wu, T.-C. Chou, S.-C. Chang and C.-L. Lin (2019). "The Prognostic Significance of Puncture Timing to Survival of Arteriovenous Fistulas in Hemodialysis Patients: A Multicenter Retrospective Cohort Study." Journal of Clinical Medicine 8(2).
  8. Peng, Y.-S., J.-R. Lin, B.-H. Cheng, C. Ho, Y.-H. Lin, C.-H. Shen and M.-H. Tsai (2019). "Incidence and relative risk for developing cancers in women with gestational diabetes mellitus: a nationwide cohort study in Taiwan." BMJ Open 9(2): e024583.
  9. Wang, C. L., P. C. Chen, H. T. Juang and C. J. Chang (2019). "Adverse Outcomes Associated with Pre-Existing and New-Onset Atrial Fibrillation in Patients with Acute Coronary Syndrome: A Retrospective Cohort Study." Cardiol Ther 8(1): 117-127.
  10. Wang, C. L., V. C. Wu, Y. T. Huang, C. F. Kuo, P. H. Chu, Y. L. Chen, M. S. Wen and S. H. Chang (2019). "Safety and Effectiveness of Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention in Patients With Atrial Fibrillation and Anemia: A Retrospective Cohort Study." J Am Heart Assoc 8(9): e012029.
  11. Weng, Y. M., C. J. Ng, C. J. Seak, C. Y. Chien, K. F. Chen, J. R. Lin and C. J. Chang (2018). "One-year survival rate and healthcare costs after cardiac arrest in Taiwan, 2006-2012." PLoS One 13(5): e0196687.
  12. Tsai, S. S., Y. Y. Chu, S. T. Chen and P. H. Chu (2018). "A comparison of different definitions of metabolic syndrome for the risks of atherosclerosis and diabetes." Diabetol Metab Syndr 10: 56.
  13. Chang, S., Y. Huang, M. Lee and et al. (2018). "Association of varicose veins with incident venous thromboembolism and peripheral artery disease." JAMA 319(8): 807-817.
  14. Lin, Y. C., C. H. Chang, C. J. Chang, Y. C. Wang, P. H. Hsieh and Y. Chang (2018). "Vascular injury during primary total knee arthroplasty: A nationwide study." J Formos Med Assoc.
  15. Lin, Y. C., S. H. Lee, I. J. Chen, C. H. Chang, C. J. Chang, Y. C. Wang, Y. Chang and P. H. Hsieh (2018). "Symptomatic pulmonary embolism following hip fracture: A nationwide study." Thromb Res 172: 120-127.
  16. Lin, Y. H., Y. Y. Huang, Y. L. Wu, C. W. Lin, P. C. Chen, C. J. Chang, S. H. Hsieh, J. H. Sun, S. T. Chen and C. H. Lin (2018). "Coadministration of DPP-4 inhibitor and insulin therapy does not further reduce the risk of cardiovascular events compared with DPP-4 inhibitor therapy in diabetic foot patients: a nationwide population-based study." Diabetol Metab Syndr 10: 75.
  17. Chou, S. H., Y. C. Tung, L. S. Wu, C. J. Chang, S. Kung and P. H. Chu (2018). "Severity of chronic periodontitis and risk of gastrointestinal cancers: A population-based follow-up study from Taiwan." Medicine (Baltimore) 97(27): e11386.
  18. Chang, Y.-H., S.-W. Chang, C.-Y. Liu, P.-H. Lin, K.-J. Yu, S.-T. Pang, C.-K. Chuang, H.-C. Kan and I. H. Shao (2018). "Demographic characteristics and complications of open and minimally invasive surgeries for renal cell carcinoma: a population-based case-control study in Taiwan." Therapeutics and clinical risk management 14: 1235-1241.
  19. Chang, C.-C., S.-H. Chen, T.-Y. Chang, C.-J. Wang, W. Yang, C.-J. Chang and T.-H. Jaing (2018). "Relationship between the Computed Tomography - Measured Initial Primary Tumor Volume, Urine VMA Level and Stage in Neuroblastoma Patients." Iran J Radiol 15(3): e63270.
  20. Li, C. Y., C. J. Chang, W. J. Chung, C. J. Lin, S. K. Hsueh, C. H. Lee, C. J. Wu, T. H. Tsai and C. I. Cheng (2018). "Assessment of CHA2DS2-VASc score for predicting cardiovascular and cerebrovascular outcomes in acute myocardial infarction patients." Medicine (Baltimore) 97(28): e11230.
  21. Liu, L., I. Enkh-Amgalan, N. K. Wang, L. H. Chuang, Y. P. Chen, Y. S. Hwang, C. J. Chang, K. J. Chen, W. C. Wu, T. L. Chen and C. C. Lai (2018). "RESULTS OF MACULAR HOLE SURGERY: Evaluation Based on the International Vitreomacular Traction Study Classification." Retina 38(5): 900-906.
  22. Kuo, F. C., C. J. Chang, K. L. Bell, M. S. Lee and J. W. Wang (2018). "No Difference in Morbidity and Mortality After Total Joint Arthroplasty in Liver Transplant Recipients: A Propensity Score-Matched Analysis of a Nationwide, Population-Based Study Using Universal Healthcare Data." J Arthroplasty.
  23. Kuo, G., W. C. Sun, Y. A. Lu, C. Y. Chen, H. K. Kao, Y. Lin, Jr., Y. C. Chen, C. C. Hung, Y. C. Tian and H. H. Hsu (2018). "Chronic dialysis patients with infectious spondylodiscitis have poorer outcomes than non-dialysis populations." Ther Clin Risk Manag 14: 257-263.
  24. Li, Y.-H., Y.-H. Chen, K.-J. Chen, N.-K. Wang, M.-H. Sun, A.-N. Chao, L. Liu, Y. Lin, Jr., W.-C. Wu, Y.-S. Hwang, C.-C. Lai and T.-L. Chen (2018). "Infectious Sources, Prognostic Factors, and Visual Outcomes of Endogenous <em>Klebsiella pneumoniae</em> Endophthalmitis." Ophthalmology Retina 2(8): 771-778.
  25. Lai, Y.-R., J.-R. Lin, W.-N. Chang, N.-W. Tsai, C.-C. Huang, H.-C. Wang, Y.-J. Su, W.-C. Lin, B.-C. Cheng, C.-M. Su, S.-Y. Hsiao, C.-E. Kuo and C.-H. Lu (2018). "Outcomes of adjunctive steroid therapy in adult patients with bacterial meningitis in Taiwan: A nationwide population-based epidemiologic study." Journal of Clinical Neuroscience.
  26. Lu, Y. A., W. C. Sun, G. Kuo, C. Y. Chen, H. K. Kao, Y. Lin, C. H. Lee, C. C. Hung, Y. C. Tian, Y. S. Ko and H. H. Hsu (2018). "Epidemiology and Outcomes of Infectious Spondylodiscitis in Hemodialysis Patients." Spine (Phila Pa 1976) 43(12): 869-876.
  27. Lu, Y. A., K. H. Tu, C. C. Lee, P. W. Wu, C. J. Chang, Y. C. Tian, C. W. Yang and P. H. Chu (2017). "Prognostic impact of peritonitis in hemodialysis patients: A national-wide longitudinal study in Taiwan." PLoS One 12(3): e0173710.
  28. Mahmoudi, E., Y. Lu, S. C. Chang, C. Y. Lin, Y. C. Wang, C. J. Chang, M. H. Cheng and K. C. Chung (2017). "The Associations of Hospital Volume, Surgeon Volume, and Surgeon Experience with Complications and 30-Day Rehospitalization after Free Tissue Transfer: A National Population Study." Plast Reconstr Surg 140(2): 403-411.
  29. Mahmoudi, E., Y. Lu, S.-C. Chang, C.-Y. Lin, Y.-C. Wang, C. J. Chang, M.-H. Cheng and K. C. Chung (2017). "Association of High-Volume Surgeons Working in High-Volume Hospitals with Cost of Free Flap Surgeries." Plastic and Reconstructive Surgery Global Open 5(10): e1520.
  30. Mahmoudi, E., Y. Lu, S. C. Chang, C. Y. Lin, Y. C. Wang, C. J. Chang, M. H. Cheng and K. C. Chung (2017). "Associations of Surgeon and Hospital Volumes with Outcome for Free Tissue Transfer by Using the National Taiwan Population Health Care Data from 2001 to 2012." Plast Reconstr Surg 140(3): 455e-465e.
  31. Lu, C. Y., H. C. Huang, H. H. Chang, T. H. Yang, C. J. Chang, S. W. Chang and P. C. Chen (2017). "Acupuncture Therapy and Incidence of Depression After Stroke." Stroke 48(6): 1682-1684.
  32. Chen, W. T., M. S. Lee, C. L. Chang, C. T. Chiu and M. L. Chang (2017). "Retinol-binding protein-4 expression marks the short-term mortality of critically ill patients with underlying liver disease: Lipid, but not glucose, matters." Sci Rep 7(1): 2881.
  33. Ni, H. C., J. Hung, C. T. Wu, Y. Y. Wu, C. J. Chang, R. S. Chen and Y. Z. Huang (2017). "The Impact of Single Session Intermittent Theta-Burst Stimulation over the Dorsolateral Prefrontal Cortex and Posterior Superior Temporal Sulcus on Adults with Autism Spectrum Disorder." Front Neurosci 11: 255.
  34. Liao, C. T., Y. W. Wen, S. R. Lee, T. W. Liu, S. T. Tsai, M. H. Tsai, J. C. Lin, P. J. Lou, P. Y. Chu, Y. S. Leu, K. Y. Tsai, S. D. Terng, T. M. Chen, C. H. Wang, C. Y. Chien, W. C. Chen, L. Y. Lee, C. Y. Lin, H. M. Wang, S. H. Ng, C. H. Lin, T. J. Fang, S. F. Huang, C. J. Kang, K. P. Chang, L. Y. Yang and T. C. Yen (2017). "Clinical Outcomes of Taiwanese Patients with cT4 Oral Cavity Squamous Cell Carcinoma: Toward the Identification of the Optimal Initial Treatment Approach for cT4b Patients." Ann Surg Oncol 24(3): 785-793.
  35. Liao, C. T., H. N. Chen, Y. W. Wen, S. R. Lee, S. H. Ng, T. W. Liu, S. T. Tsai, M. H. Tsai, J. C. Lin, P. J. Lou, C. P. Wang, P. Y. Chu, Y. S. Leu, K. Y. Tsai, S. D. Terng, T. M. Chen, C. H. Wang, C. Y. Chien, W. C. Chen, L. Y. Lee, C. Y. Lin, H. M. Wang, C. H. Lin, T. J. Fang, S. F. Huang, C. J. Kang, K. P. Chang, L. Y. Yang and T. C. Yen (2017). "Association between the diagnosis-to-treatment interval and overall survival in Taiwanese patients with oral cavity squamous cell carcinoma." Eur J Cancer 72: 226-234.
  36. Liao, C. T., Y. W. Wen, L. Y. Yang, S. R. Lee, S. H. Ng, T. W. Liu, S. T. Tsai, M. H. Tsai, J. C. Lin, P. R. Chen, P. J. Lou, C. P. Wang, P. Y. Chu, T. Z. Hwang, Y. S. Leu, K. Y. Tsai, S. D. Terng, T. M. Chen, C. H. Wang, C. Y. Chien, W. C. Chen, L. Y. Lee, C. Y. Lin, H. M. Wang, C. H. Hsieh, C. K. Tsao, T. J. Fang, S. F. Huang, C. J. Kang, K. P. Chang and T. C. Yen (2017). "Comparative clinical outcomes of Taiwanese patients with resected buccal and tongue squamous cell carcinomas." Oral Oncol 67: 95-102.
  37. Ying-Chang Tung, Yu-Chang Huang, Lung-Sheng, Chee-Jen Chang, Pao-Hsien Chu. Medication compliance and clinical outcomes of fixed- dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment. J Clin Hypertens 2017
  38. Chang, M. L., C. M. Hsu, C. H. Lin, C. Y. Lin, C. J. Kuo, S. W. Huang, C. W. Chen, H. T. Cheng, C. T. Yeh and C. T. Chiu (2017). "The Evolving Interplay among Abundant Adipokines in Patients with Hepatitis C during Viral Clearance." Nutrients 9(6).
  39. Chen K-F, Liu S-H, Li C-H, Wu C-C, Chaou C-H, Tzeng IS, et al. Development and validation of a parsimonious and pragmatic CHARM score to predict mortality in patients with suspected sepsis. The American Journal of Emergency Medicine. 2017;35(4):640-6.
  40. Yeo LLL, Chien SC, Lin JR, Liow CW, Lee JD, Peng TI, et al. Derivation and Validation of a Scoring System for Intravenous Tissue Plasminogen Activator Use in Asian Patients. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2017;26(8):1695-703.
  41. Chien CY, Chen YH, Han ST, Blaney GN, Huang TS, Chen KF. The number of displaced rib fractures is more predictive for complications in chest trauma patients. Scandinavian journal of trauma, resuscitation and emergency medicine. 2017;25(1):19.
  42. Fife D, Feng Y, Wang MY, Chang CJ, Liu CY, Juang HT, et al. Epidemiology of pharmaceutically treated depression and treatment resistant depression in Taiwan. Psychiatry research. 2017;252:277-83.
  43. Lin YS, Liu PH, Lin SW, Chuang LP, Ho WJ, Chou YT, et al. Simple obstructive sleep apnea patients without hypertension or diabetes accelerate kidney dysfunction: a population follow-up cohort study from Taiwan. Sleep & breathing = Schlaf & Atmung. 2017;21(1):85-91.
  44. Chao H-Y, Liu P-H, Lin S-C, Chen C-K, Chen J-C, Chan Y-L, et al. Association of In-Hospital Mortality and Dysglycemia in Septic Patients. PLoS ONE. 2017;12(1):e0170408.
  45. 探討飲食行為控制對第2型糖尿病患者臨床血液生化值之影響 / 台灣營養學會雜誌 /2017
  46. Hong, C. H., H. P. Tu, J. R. Lin and C. H. Lee (2016). "An estimation of the incidence of tuberous sclerosis complex in a nationwide retrospective cohort study (1997-2010)." Br J Dermatol 174(6): 1282-1289.
  47. Lai CC, Lin TH, Yip HK, Liu CP, Li AH, Shyu KG, et al. One-year cardiovascular outcomes of drug-eluting stent versus bare-metal stent implanted in diabetic patients with acute coronary syndrome. Journal of the Chinese Medical Association : JCMA. 2016;79(5):239-47.
  48. Ho W-M, Lin J-R, Wang H-H, Liou C-W, Chang K-C, Lee J-D, et al. Prediction of in-hospital stroke mortality in critical care unit. SpringerPlus. 2016;5(1):1051.
  49. Chen FP, Chang CJ, Chao AS, Huang HY, Huang JP, Wu MH, et al. Efficacy of Femarelle for the treatment of climacteric syndrome in postmenopausal women: An open label trial. Taiwanese journal of obstetrics & gynecology. 2016;55(3):336-40.
  50. Ku CL, Lin CH, Chang SW, Chu CC, Chan JF, Kong XF, et al. Anti-IFN-gamma autoantibodies are strongly associated with HLA-DR*15:02/16:02 and HLA-DQ*05:01/05:02 across Southeast Asia. The Journal of allergy and clinical immunology. 2016;137(3):945-8.e8.
  51. Yao TC, Chang SW, Hua MC, Liao SL, Tsai MH, Lai SH, et al. Tobacco smoke exposure and multiplexed immunoglobulin E sensitization in children: a population-based study. Allergy. 2016;71(1):90-8.
  52. Chung PC-H, Chen H-P, Lin J-R, Liu F-C, Yu H-P. Impact of preoperative chronic renal failure on liver transplantation: a population-based cohort study. Therapeutics and Clinical Risk Management. 2016;12:1855-60.
  53. Chang C-H, Lee C-C, Chen S-W, Fan P-C, Chen Y-C, Chang S-W, et al. Predicting Acute Kidney Injury Following Mitral Valve Repair. International Journal of Medical Sciences. 2016;13(1):19-24.
  54. Ng CY, Yeh YT, Wang CW, Hung SI, Yang CH, Chang YC, et al. Impact of the HLA-B(*)58:01 Allele and Renal Impairment on Allopurinol-Induced Cutaneous Adverse Reactions. The Journal of investigative dermatology. 2016;136(7):1373-81.
  55. Tsai YF, Chen HP, Liu FC, Liu SH, Chen CY, Cheng CW, et al. Nationwide population-based study reveals increased malignancy risk in taiwanese liver transplant recipients. Oncotarget. 2016;7(50):83784-94.
  56. Chang PY, Zeng Q, Wong KS, Wang CJ, Chang CJ. Chest Wall Constriction after the Nuss Procedure Identified from Chest Radiograph and Multislice Computed Tomography Shortly after Removal of the Bar. Thorac Cardiovasc Surg. 2016;64(1):70-7
  57. Yang CH, Chang CH, Chen TH, Fan PC, Chang SW, Chen CC, et al. Combination of Urinary Biomarkers Improves Early Detection of Acute Kidney Injury in Patients With Heart Failure. Circulation journal : official journal of the Japanese Circulation Society. 2016;80(4):1017-23.
  58. Chen HP, Tsai YF, Lin JR, Liu FC, Yu HP. Recipient Age and Mortality Risk after Liver Transplantation: A Population-Based Cohort Study. PLoS One. 2016;11(3):e0152324.
  59. Chen SW, Chang CH, Fan PC, Chen YC, Chu PH, Chen TH, et al. Comparison of contemporary preoperative risk models at predicting acute kidney injury after isolated coronary artery bypass grafting: a retrospective cohort study. BMJ open. 2016;6(6):e010176.
  60. Lin TC, Mao SH, Chen CH, Chen YL, Wong HF, Chang CJ, et al. Systematic Analysis of the Risk Factors Affecting the Recurrence of Traumatic Carotid-Cavernous Sinus Fistula. World neurosurgery. 2016;90:539-45.e1.
  61. Chen CK, Lin SC, Wu CC, Chen LM, Tzeng IS, Chen KF. STARD-compliant article: The utility of red cell distribution width to predict mortality for septic patients visiting the emergency department. Medicine. 2016;95(24):e3692.
  62. Chen, K. F., C. H. Chaou, J. Y. Jiang, H. W. Yu, Y. H. Meng, W. C. Tang and C. C. Wu (2016). "Diagnostic Accuracy of Lipopolysaccharide-Binding Protein as Biomarker for Sepsis in Adult Patients: A Systematic Review and Meta-Analysis." PLoS One 11(4): e0153188.
  63. Cheng, C. W., F. C. Liu, J. R. Lin, Y. F. Tsai, H. P. Chen and H. P. Yu (2016). "The Impact of Hospital/Surgeon Volume on Acute Renal Failure and Mortality in Liver Transplantation: A Nationwide Cohort Study." PLoS One 11(10): e0162992.
  64. Chou, H. L., S. T. Han, C. F. Yeh, I. S. Tzeng, T. H. Hsieh, C. C. Wu, J. T. Kuan and K. F. Chen (2016). "Systemic inflammatory response syndrome is more associated with bacteremia in elderly patients with suspected sepsis in emergency departments." Medicine (Baltimore) 95(49): e5634.
  65. Hsu, C. Y., S. H. Liu, C. H. Chao, Y. L. Chan, T. C. Tsai, L. M. Chen, C. C. Wu and K. F. Chen (2016). "STROBE-compliant article: Blood Transfusions within the First 24 Hours of Hospitalization Did Not Impact Mortality Among Patients with Severe Sepsis." Medicine (Baltimore) 95(4): e2601.
  66. Liu, F. C., J. R. Lin, H. P. Chen, Y. F. Tsai and H. P. Yu (2016). "Prevalence, predictive factors, and survival outcome of new-onset diabetes after liver transplantation: A population-based cohort study." Medicine (Baltimore) 95(25): e3829.
  67. Tzeng, I. S., S. H. Liu, Y. T. Chiou, C. H. Huang, C. J. Lee, C. Y. Chien, S. C. Hsu, Y. M. Weng, K. F. Chen and J. C. Chen (2016). "Predicting emergency departments visit rates from septicemia in Taiwan using an age-period-cohort model, 1998 to 2012." Medicine (Baltimore) 95(50): e5598.
  68. Chang P-Y, Zeng Q, Wong K-S, Lai J-Y, Chen J-C, Wang C-J, et al. A Cross-Sectional Study of Chest Wall Development in Patients with Pectus Excavatum. Thorac cardiovasc Surg. 2015;63(05):433-6.
  69. Chang CH, Fan PC, Lin CY, Yang CH, Chen YT, Chang SW, et al. Elevation of Interleukin-18 Correlates With Cardiovascular, Cerebrovascular, and Peripheral Vascular Events: A Cohort Study of Hemodialysis Patients. Medicine. 2015;94(42):e1836.
  70. Tung YC, Lin YS, Wu LS, Chang CJ, Chu PH. Clinical outcomes and healthcare costs in hypertensive patients treated with a fixed-dose combination of amlodipine/valsartan. Journal of clinical hypertension (Greenwich, Conn). 2015;17(1):51-8.
  71. Cheng JS, Tsai WC, Lin CL, Chen L, Lang HC, Hsieh HM, et al. Trend and factors associated with healthcare use and costs in type 2 diabetes mellitus: a decade experience of a universal health insurance program. Medical care. 2015;53(2):116-24.
  72. Tsai YH, Hsieh MJ, Chang CJ, Wen YW, Hu HC, Chao YN, et al. The 23-valent pneumococcal polysaccharide vaccine is effective in elderly adults over 75 years old--Taiwan's PPV vaccination program. Vaccine. 2015;33(25):2897-902.
  73. Li C-Y, Lin C-P, Lin Y-S, Wu L-S, Chang C-J, Chu P-H. Newly Diagnosed Atrial Fibrillation Is an Independent Factor for Future Major Adverse Cardiovascular Events. PLoS ONE. 2015;10(4):e0123211.
  74. Tsai HC, Chang CH, Tsai FC, Fan PC, Juan KC, Lin CY, et al. Acute Respiratory Distress Syndrome With and Without Extracorporeal Membrane Oxygenation: A Score Matched Study. The Annals of thoracic surgery. 2015;100(2):458-64.
  75. Lai C-C, Chang K-C, Liao P-C, Wu C-T, Lai W-T, Wu C-J, et al. Effects of Door-to-Balloon Times on Outcomes in Taiwanese Patients Receiving Primary Percutaneous Coronary Intervention: A Report of Taiwan Acute Coronary Syndrome Full Spectrum Registry. Acta Cardiologica Sinica. 2015;31(3):215-25
  76. Lin J.R., Chang Y.C., and Liu J.P. Evaluation of the Parallel Line Assay for Assessment of Biosimilar Products Based on Censored Data. Journal of the Chinese Statistical Association. 2015;53(1):23-37.
  77. Wen Y-W, Wu H, Chang C-J. Using Dynamic Transmission Modeling to Determine Vaccination Coverage Rate Based on 5-Year Economic Burden of Infectious Disease: An Example of Pneumococcal Vaccine. Value in Health Regional Issues. 2015;6:46-52.
  78. Chang, C. H., C. H. Yang, H. Y. Yang, T. H. Chen, C. Y. Lin, S. W. Chang, Y. T. Chen, C. C. Hung, J. T. Fang, C. W. Yang and Y. C. Chen (2015). "Urinary Biomarkers Improve the Diagnosis of Intrinsic Acute Kidney Injury in Coronary Care Units." Medicine (Baltimore) 94(40): e1703.
  79. Chen, H. P., Y. F. Tsai, J. R. Lin, F. C. Liu and H. P. Yu (2015). "Incidence and Outcomes of Acute Renal Failure Following Liver Transplantation: A Population-Based Cohort Study." Medicine (Baltimore) 94(52): e2320.
  80. Chang S-W, Fann CS-J, Su W-H, Wang YC, Weng CC, Yu C-J, et al. A Genome-Wide Association Study on Chronic HBV Infection and Its Clinical Progression in Male Han-Taiwanese. PLOS ONE. 2014;9(6):e99724
  81. Lai C-C, Yip H-K, Lin T-H, Wu C-J, Lai W-T, Liu C-P, et al. Drug-Eluting Stents versus Bare-Metal Stents in Taiwanese Patients with Acute Coronary Syndrome: An Outcome Report of a Multicenter Registry. Acta Cardiologica Sinica. 2014;30(6):553-64.
  82. Chen J-Y, Wang C-M, Chang S-W, Cheng C-H, Wu Y-JJ, Lin J-C, et al. Association of FCGR3A and FCGR3B Copy Number Variations With Systemic Lupus Erythematosus and Rheumatoid Arthritis in Taiwanese Patients. Arthritis & Rheumatology (Hoboken, Nj). 2014;66(11):3113-21.
  83. Huang T-P, Liu P-H, Lien AS-Y, Yang S-L, Chang H-H, Yen H-R. A nationwide population-based study of traditional Chinese medicine usage in children in Taiwan. Complementary Therapies in Medicine. 2014;22(3):500-10.
  84. Cheung Y-C, Lin Y-C, Wan Y-L, Yeow K-M, Huang P-C, Lo Y-F, et al. Diagnostic performance of dual-energy contrast-enhanced subtracted mammography in dense breasts compared to mammography alone: interobserver blind-reading analysis. European Radiology. 2014;24(10):2394-403.
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