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研究成果

  為積極推廣健康資料研究至長庚醫院,提升臨床醫師、專任人員對健康資料應用研究之熱情,並鼓勵研究資源相對不足之年輕醫師或研究人員投入其研究,本中心向長庚醫院申請之多年期整合型計畫(CMRP),結合專業研究群,提供協作服務並幫助已收集臨床資料之醫師與現有健康庫整合比對,拓展健康資料應用之加值效益,透過雙方合作與成果,提升長庚大學及長庚醫院之知名度,目前已有31篇論文發表,其中1篇研究成果於20182月發表於世界頂尖醫學期刊「美國醫學會雜誌(JAMA: The Journal of the American Medical Association)」,同時於校內的榮譽消息專區/長庚校訊做了報導   靜脈曲張可能造成深層靜脈血栓之嚴重後果─長庚醫院與長庚大學研究合作榮登美國醫學會雜誌。

本中心CMRP現研究成果如下:

  1. Chang S, Huang Y, Lee M, et al. Association of varicose veins with incident venous thromboembolism and peripheral artery disease. JAMA. 2018;319(8):807-17.
  2. Lin MJ, Chen HW, Liu PH, Cheng WJ, Kuo SL, Kao MC. The prescription patterns of traditional Chinese medicine for women with polycystic ovary syndrome in Taiwan: A nationwide population-based study. Medicine. 2019;98(24):e15890.
  3. Wang CL, Wu VC, Huang YT, Kuo CF, Chu PH, Chen YL, et al. Safety and Effectiveness of Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention in Patients With Atrial Fibrillation and Anemia: A Retrospective Cohort Study. Journal of the American Heart Association. 2019;8(9):e012029.
  4. Wang CL, Chen PC, Juang HT, Chang CJ. Adverse Outcomes Associated with Pre-Existing and New-Onset Atrial Fibrillation in Patients with Acute Coronary Syndrome: A Retrospective Cohort Study. Cardiology and therapy. 2019;8(1):117-27.
  5. Lin HC, Lai CC, Lin PW, Friedman M, Salapatas AM, Chang HW, et al. Clinical Prediction Model for Obstructive Sleep Apnea among Adult Patients with Habitual Snoring. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2019:194599819839999.
  6. Chen CH, Chen CB, Chang CJ, Lin YJ, Wang CW, Chi CC, et al. Hypersensitivity and cardiovascular risks related to allopurinol and febuxostat therapy in Asians: A population-based cohort study and meta-analysis. Clinical pharmacology and therapeutics. 2019.
  7. Lin S-J, Tung C-W, Hsu Y-C, Shih Y-H, Wu Y-L, Chou T-C, et al. The Prognostic Significance of Puncture Timing to Survival of Arteriovenous Fistulas in Hemodialysis Patients: A Multicenter Retrospective Cohort Study. Journal of Clinical Medicine. 2019;8(2).
  8. Peng Y-S, Lin J-R, Cheng B-H, Ho C, Lin Y-H, Shen C-H, et al. Incidence and relative risk for developing cancers in women with gestational diabetes mellitus: a nationwide cohort study in Taiwan. BMJ Open. 2019;9(2):e024583.
  9. Chang Y-H, Chang S-W, Liu C-Y, Lin P-H, Yu K-J, Pang S-T, et al. Demographic characteristics and complications of open and minimally invasive surgeries for renal cell carcinoma: a population-based case-control study in Taiwan. Therapeutics and clinical risk management. 2018;14:1235-41.
  10. Lai Y-R, Lin J-R, Chang W-N, Tsai N-W, Huang C-C, Wang H-C, et al. Outcomes of adjunctive steroid therapy in adult patients with bacterial meningitis in Taiwan: A nationwide population-based epidemiologic study. Journal of Clinical Neuroscience. 2018.
  11. Lin YC, Lee SH, Chen IJ, Chang CH, Chang CJ, Wang YC, et al. Symptomatic pulmonary embolism following hip fracture: A nationwide study. Thrombosis research. 2018;172:120-7.
  12. Lin YH, Huang YY, Wu YL, Lin CW, Chen PC, Chang CJ, et al. Coadministration of DPP-4 inhibitor and insulin therapy does not further reduce the risk of cardiovascular events compared with DPP-4 inhibitor therapy in diabetic foot patients: a nationwide population-based study. Diabetology & metabolic syndrome. 2018;10:75.
  13. Li Y-H, Chen Y-H, Chen K-J, Wang N-K, Sun M-H, Chao A-N, et al. Infectious Sources, Prognostic Factors, and Visual Outcomes of Endogenous <em>Klebsiella pneumoniae</em> Endophthalmitis. Ophthalmology Retina. 2018;2(8):771-8.
  14. Tsai SS, Chu YY, Chen ST, Chu PH. A comparison of different definitions of metabolic syndrome for the risks of atherosclerosis and diabetes. Diabetology & metabolic syndrome. 2018;10:56.
  15. Lu YA, Sun WC, Kuo G, Chen CY, Kao HK, Lin Y, et al. Epidemiology and Outcomes of Infectious Spondylodiscitis in Hemodialysis Patients. Spine. 2018;43(12):869-76.
  16. Chou SH, Tung YC, Wu LS, Chang CJ, Kung S, Chu PH. Severity of chronic periodontitis and risk of gastrointestinal cancers: A population-based follow-up study from Taiwan. Medicine. 2018;97(27):e11386.
  17. Kuo FC, Chang CJ, Bell KL, Lee MS, Wang JW. No Difference in Morbidity and Mortality After Total Joint Arthroplasty in Liver Transplant Recipients: A Propensity Score-Matched Analysis of a Nationwide, Population-Based Study Using Universal Healthcare Data. The Journal of arthroplasty. 2018.
  18. Lin YC, Chang CH, Chang CJ, Wang YC, Hsieh PH, Chang Y. Vascular injury during primary total knee arthroplasty: A nationwide study. J Formos Med Assoc. 2018.
  19. Weng YM, Ng CJ, Seak CJ, Chien CY, Chen KF, Lin JR, et al. One-year survival rate and healthcare costs after cardiac arrest in Taiwan, 2006-2012. PLoS One. 2018;13(5):e0196687.
  20. Kuo G, Sun WC, Lu YA, Chen CY, Kao HK, Lin Y, Jr., et al. Chronic dialysis patients with infectious spondylodiscitis have poorer outcomes than non-dialysis populations. Ther Clin Risk Manag. 2018;14:257-63.
  21. Chang ML, Hsu CM, Lin CH, Lin CY, Kuo CJ, Huang SW, et al. The Evolving Interplay among Abundant Adipokines in Patients with Hepatitis C during Viral Clearance. Nutrients. 2017;9(6).
  22. Chen WT, Lee MS, Chang CL, Chiu CT, Chang ML. Retinol-binding protein-4 expression marks the short-term mortality of critically ill patients with underlying liver disease: Lipid, but not glucose, matters. Sci Rep. 2017;7(1):2881.
  23. Lu YA, Tu KH, Lee CC, Wu PW, Chang CJ, Tian YC, et al. Prognostic impact of peritonitis in hemodialysis patients: A national-wide longitudinal study in Taiwan. PLoS One. 2017;12(3):e0173710.
  24. Mahmoudi E, Lu Y, Chang S-C, Lin C-Y, Wang Y-C, Chang CJ, et al. Association of High-Volume Surgeons Working in High-Volume Hospitals with Cost of Free Flap Surgeries. Plastic and Reconstructive Surgery Global Open. 2017;5(10):e1520.
  25. Mahmoudi E, Lu Y, Chang SC, Lin CY, Wang YC, Chang CJ, et al. Associations of Surgeon and Hospital Volumes with Outcome for Free Tissue Transfer by Using the National Taiwan Population Health Care Data from 2001 to 2012. Plast Reconstr Surg. 2017;140(3):455e-65e.
  26. Mahmoudi E, Lu Y, Chang SC, Lin CY, Wang YC, Chang CJ, et al. The Associations of Hospital Volume, Surgeon Volume, and Surgeon Experience with Complications and 30-Day Rehospitalization after Free Tissue Transfer: A National Population Study. Plast Reconstr Surg. 2017;140(2):403-11.
  27. Lu CY, Huang HC, Chang HH, Yang TH, Chang CJ, Chang SW, et al. Acupuncture Therapy and Incidence of Depression After Stroke. Stroke. 2017;48(6):1682-4.
  28. Liao CT, Wen YW, Yang LY, Lee SR, Ng SH, Liu TW, et al. Comparative clinical outcomes of Taiwanese patients with resected buccal and tongue squamous cell carcinomas. Oral Oncol. 2017;67:95-102.
  29. Liao CT, Chen HN, Wen YW, Lee SR, Ng SH, Liu TW, et al. Association between the diagnosis-to-treatment interval and overall survival in Taiwanese patients with oral cavity squamous cell carcinoma. Eur J Cancer. 2017;72:226-34.
  30. Liao CT, Wen YW, Lee SR, Liu TW, Tsai ST, Tsai MH, et al. Clinical Outcomes of Taiwanese Patients with cT4 Oral Cavity Squamous Cell Carcinoma: Toward the Identification of the Optimal Initial Treatment Approach for cT4b Patients. Ann Surg Oncol. 2017;24(3):785-93.
  31. Hong CH, Tu HP, Lin JR, Lee CH. An estimation of the incidence of tuberous sclerosis complex in a nationwide retrospective cohort study (1997-2010). Br J Dermatol. 2016;174(6):1282-9.